P021

Research & Reconstitution Information

P021 (also referenced as P21) is a synthetic peptidomimetic derived from an active region of Ciliary Neurotrophic Factor (CNTF), designed to cross the blood-brain barrier. It has been studied in a triple-transgenic mouse model of Alzheimer's disease, where chronic treatment was associated with reduced tau hyperphosphorylation and amyloid-beta levels, increased BDNF expression, and restored hippocampal neurogenesis and memory performance in the animal model. This is a narrow evidence base — essentially one research group's published work — rather than a broad independent literature, and no human trials exist for this compound. Reconstitute with bacteriostatic water, swirl gently (do not shake), and store unreconstituted vials at 2-8°C short-term or -20°C for long-term storage. Refrigerate (2-8°C) once reconstituted. For laboratory research purposes only.

Certificate of Analysis

All products are independently tested by accredited third-party laboratories. Results confirm identity, purity, and potency.

How to Reconstitute

1. 1.Clean the vial top with an alcohol swab, then slowly release solvent along the inside wall of the vial — don't squirt directly onto the powder.
2. 2.Let it dissolve on its own for a few minutes. Swirl gently if needed — do not shake.
3. 3.Refrigerate (2-8°C) once reconstituted.

Full walkthrough and the concentration calculator: Peptide Guide →